Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Simple techniques to detect and identify phentermine adulteration.

B W Hadzija, A M Mattocks

    Forensic Science International
    |November 1, 1983
    PubMed
    Summary

    Counterfeit Ionamin capsules, suspected to contain phentermine, were found to contain caffeine and phenylpropanolamine instead. Analytical tests confirmed the absence of phentermine and the presence of these other substances, highlighting a drug authenticity issue.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Atropine overdosage with a suppository formulation containing atropine sulfate.

    International journal of pharmaceutical compounding·2013
    Same author

    Stability of four commercial products delivered by mail order.

    International journal of pharmaceutical compounding·2013
    Same author

    Hydrophilic acid ointments for the debridement of burns.

    Journal of the American Pharmaceutical Association. American Pharmaceutical Association·2010
    Same author

    A synthesis of p-aminophenylalanine.

    Journal of the American Pharmaceutical Association. American Pharmaceutical Association·2010
    Same author

    The new approach to synthetic medicinals.

    The Journal of the Alabama Academy of Science·2010
    Same author

    A synthesis of serine and its methyl ester.

    The Journal of biological chemistry·2010

    Area of Science:

    • Pharmaceutical Analysis
    • Forensic Chemistry

    Background:

    • Counterfeit medications pose significant public health risks.
    • Ensuring drug authenticity is crucial for patient safety and treatment efficacy.

    Purpose of the Study:

    • To investigate the contents of suspected counterfeit phentermine capsules (Ionamin).
    • To identify the active pharmaceutical ingredients present in the suspect medication.

    Main Methods:

    • Spectrophotometric identity tests were performed.
    • Microcrystalline and spectrodensitometry analyses were utilized for confirmation.

    Main Results:

    • Phentermine was not detected in the analyzed capsules.
    • Caffeine and phenylpropanolamine were identified as the primary components.

    Related Experiment Videos

  • Analytical methods confirmed the absence of phentermine.

    • Conclusions:

    • The examined Ionamin capsules were counterfeit, containing undeclared substances.
    • The findings underscore the importance of rigorous analytical testing to detect fraudulent pharmaceuticals.