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Intracellular catabolin-like activity in cultured synovial tissue
In Vitro
|December 1, 1983
Abstract:
The time course of the synthesis and secretion of catabolin-like activity by porcine synovial tissue was determined. Ex vivo tissue had no demonstrable activity, but short-term culture (less than 1 h) induced cellular accumulation of activity. This accumulation, which preceded secretion, was reversibly inhibited by cycloheximide. The activity was localized in the cystol fraction.