Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Regulation of Heart Rates01:31

Regulation of Heart Rates

3.7K
The regulation of heart rate is a complex process controlled by the autonomic nervous system (ANS), hormonal influences, and intrinsic cardiac mechanisms. The ANS has two main components: the sympathetic nervous system (SNS) and the parasympathetic nervous system (PNS).
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...
3.7K
Neural Regulation of Blood Pressure01:18

Neural Regulation of Blood Pressure

6.8K
The neural regulation of blood pressure involves intricate interactions between the autonomic nervous system (ANS) and cardiovascular system, ensuring adequate perfusion of tissues. This regulation primarily occurs through baroreceptor and chemoreceptor reflexes, involving both short-term and long-term mechanisms.
Baroreceptor Reflex
Baroreceptors, located in the carotid sinuses and aortic arch, detect changes in blood pressure. When blood pressure rises, these stretch-sensitive receptors...
6.8K
Regulation of the Cardiovascular System01:27

Regulation of the Cardiovascular System

3.6K
The regulation of the cardiovascular system allows the body to adapt to various demands and maintain homeostasis.
The regulation of the cardiovascular system involves the autonomic nervous system (ANS), baroreceptors, and chemoreceptors, ensuring that heart rate and blood pressure are appropriately modulated in response to varying physiological demands.
The ANS comprises two main divisions: the sympathetic and parasympathetic nervous systems. The sympathetic nervous system enhances...
3.6K
Other Factors Affecting Respiration Centers01:17

Other Factors Affecting Respiration Centers

1.4K
Breathing is primarily an involuntary activity regulated by the brainstem respiratory centers. However, it can also be consciously controlled, allowing us to hold our breath or take deeper breaths when needed. This voluntary control is facilitated by the cerebral motor cortex, which bypasses the medullary centers to stimulate the respiratory muscles directly.
However, the ability to hold one's breath voluntarily is not limitless. When the CO2 concentration in the blood reaches a critical...
1.4K
Factors Influencing Heart Rate01:30

Factors Influencing Heart Rate

6.1K
The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
6.1K
The Parasympathetic Nervous System01:14

The Parasympathetic Nervous System

114.7K
Overview
114.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Automated analysis of finger blood pressure recordings provides insight in determinants of baroreflex sensitivity and heart rate variability-the HELIUS study.

Medical & biological engineering & computing·2023
Same author

Autonomic Dysfunction Precedes Development of Rheumatoid Arthritis: A Prospective Cohort Study.

EBioMedicine·2016
Same author

Nonmuscle myosin heavy chain-B expression in balloon-dilated and stented arteries: a study in the atherosclerotic Yucatan micropig.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·2015
Same author

Off-pump coronary artery bypass surgery compared with stent implantation and on-pump bypass surgery: clinical outcome and cost-effectiveness at one year.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·2015
Same author

Possibilities and limitations of capillary electropherosis in pharmaceutical analysis.

Die Pharmazie·2013
Same author

Transmission of angiosarcomas from a common multiorgan donor to four transplant recipients.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2012

Related Experiment Videos

Time delays in the human baroreceptor reflex.

C Borst, J M Karemaker

    Journal of the Autonomic Nervous System
    |November 1, 1983
    PubMed
    Summary

    Electrical stimulation of carotid sinus nerves (CSN) in coronary artery disease patients reveals reflex responses. Latencies for heart rate and blood pressure changes indicate central processing time for baroreceptor activity.

    Area of Science:

    • Cardiovascular Physiology
    • Neuroscience

    Background:

    • Coronary artery disease (CAD) affects cardiovascular regulation.
    • Carotid sinus nerve (CSN) stimulation influences autonomic control of the heart and blood vessels.

    Purpose of the Study:

    • To investigate the latency of reflex cardiovascular responses to electrical CSN stimulation in patients with CAD.
    • To estimate the central processing time for baroreceptor afferent activity.

    Main Methods:

    • Low-intensity electrical stimulation of CSN, triggered by the R-wave, was applied in 11 normotensive subjects with CAD.
    • Latencies for changes in PP-interval (heart rate), AV-interval, and diastolic arterial pressure were measured.
    • Responses were assessed during both stimulation onset and cessation.

    Related Experiment Videos

    Main Results:

    • PP-interval prolongation onset occurred after a latency of 0.5–0.6 seconds.
    • AV-interval prolongation began after approximately 1 second.
    • Diastolic arterial pressure changes initiated after 2–3 seconds when heart rate was fixed.
    • Latencies were independent of respiratory phase and afferent activity direction.

    Conclusions:

    • Reflex cardiovascular responses to CSN stimulation exhibit distinct latencies.
    • Central processing of baroreceptor afferent activity is estimated to require approximately 0.25 seconds in humans.
    • These findings contribute to understanding autonomic regulation in CAD.