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Related Experiment Videos

Acrodermatitis and acquired zinc deficiency.

R I Ecker, A L Schroeter

    Archives of Dermatology
    |June 1, 1978
    PubMed
    Summary

    This study details a patient with acquired zinc deficiency due to chronic alcohol abuse and cirrhosis. Oral zinc sulfate effectively treated her acrodermatitis, which resisted topical steroids.

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    Area of Science:

    • Dermatology
    • Nutritional Science
    • Hepatology

    Background:

    • Chronic alcohol abuse can lead to malnutrition and deficiencies in essential minerals.
    • Cirrhosis, a consequence of alcohol abuse, impairs nutrient absorption and metabolism.
    • Zinc deficiency is a recognized complication of malnutrition and liver disease.

    Observation:

    • A 42-year-old female patient presented with symptoms of malnutrition.
    • She had a history of chronic alcohol (ethanol) abuse and diagnosed cirrhosis.
    • The patient exhibited acrodermatitis unresponsive to topical corticosteroid treatment.

    Findings:

    • Serum and urinary zinc levels were significantly low, confirming zinc deficiency.
    • Treatment with topical triamcinolone acetonide did not resolve the acrodermatitis.
    • Oral zinc sulfate administration led to the complete resolution of her skin condition.

    Implications:

    • This case highlights the importance of assessing zinc status in patients with alcohol-related liver disease.
    • Oral zinc supplementation can be a crucial therapeutic intervention for specific dermatological manifestations of zinc deficiency.
    • Early diagnosis and management of zinc deficiency can prevent or reverse associated complications.

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