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Related Experiment Videos

Accidental intra-arterial injection.

J M Wynne, G L Williams, B A Ellman

    Archives of Disease in Childhood
    |May 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Accidental intra-arterial antibiotic injection in infants can cause limb gangrene and neurological issues. Using shorter needles and injecting in the thigh minimizes these risks.

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    Area of Science:

    • Pediatrics
    • Pharmacology
    • Vascular Surgery

    Background:

    • Intramuscular antibiotic injections are common in pediatric care.
    • Accidental intra-arterial injection can lead to severe complications.

    Observation:

    • Three infant cases of accidental intra-arterial injection of benzathine penicillin and rolitetracycline are presented.
    • Clinical manifestations included arteriolar obstruction leading to limb gangrene and neurological deficits.

    Findings:

    • Arteriolar obstruction is the primary consequence of accidental intra-arterial antibiotic injection.
    • Involvement of vessels supplying nerves or the spinal cord can result in neurological complications.

    Implications:

    • The anterolateral thigh is a safer site for intramuscular injections than the buttock.

    Related Experiment Videos

  • Using a short needle (2.5 cm) can significantly reduce the risk of intra-arterial injection in infants.