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[Lymphogranulomatosis in childhood]
Zentralblatt Fur Allgemeine Pathologie U. Pathologische Anatomie
|January 1, 1983
Summary
This study reclassified Hodgkin's disease in 66 children, finding mixed cellularity most common and a male predominance in younger patients. Results are compared with existing literature.
Area of Science:
- Pediatric Oncology
- Hematopathology
- Childhood Hodgkin's Lymphoma
Context:
- Hodgkin's disease is uncommon in pediatric populations.
- Analysis of 66 pediatric Hodgkin's disease lymph node biopsies.
- Focus on age and sex distribution of histologic subtypes.
Purpose:
- To reclassify pediatric Hodgkin's disease lymph node biopsies.
- To analyze the relationship between age, sex, and histologic subtype.
- To compare findings with existing literature.
Summary:
- Mixed cellularity was the most frequent subtype (37.9%), with a male predominance.
- Nodular sclerosis (31.8%) and lymphocyte predominant (19.7%) were also common.
- Lymphocyte depletion was the least common subtype (6.1%).
- Hodgkin's disease showed a higher prevalence in boys aged 2-10 years.
Impact:
- Provides updated classification and epidemiological data for pediatric Hodgkin's disease.
- Aids in understanding the specific characteristics of childhood Hodgkin's lymphoma.
- Informs clinical management and further research in pediatric oncology.