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Updated: Aug 13, 2026

Preparation and Pathogen Inactivation of Double Dose Buffy Coat Platelet Products using the INTERCEPT Blood System
Published on: December 7, 2012
[New aspects of therapy with blood and blood components]
For diminishing transfusion risks and for ethical and economical reasons a rational hemotherapy is indispensable. The "Berner model" referred to here contains an acceptable explanation. It is evident that the overwhelming part of surgical interventions is accomplished by using erythrocyte concentrates. Therefore, fresh whole blood and fresh frozen plasma are better available. Coagulational active plasma fractions have unchanged indications for a rational substitution of coagulation factors. New indications for some blood components are described.
For diminishing transfusion risks and for ethical and economical reasons a rational hemotherapy is indispensable. The "Berner model" referred to here contains an acceptable explanation. It is evident that the overwhelming part of surgical interventions is accomplished by using erythrocyte concentrates. Therefore, fresh whole blood and fresh frozen plasma are better available. Coagulational active plasma fractions have unchanged indications for a rational substitution of coagulation factors. New indications for some blood components are described.
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