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Updated: Oct 13, 2026

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
Published on: June 15, 2019
[Endotoxic shock in surgical practice]
Abstract:
The authors present patients who have had an endotoxic shock from various types of septic infections in the peritoneal cavity (ulcus perforatum, appendicitis perforata, cholecystitis purulenta, acute obstruction of the intestine, pleural empyema, bronchiectasiae, pulmonary abscess etc.). The author's intention is to indicate that the etiological factors can be different, and the pathophysiological and clinical treatment have certain specific characteristics. The basic pathophysiological postulates are: severe haemodynamic disorders and numerous functional troubles and disorders of certain organs and tissue's systems. Thereby, the therapy should always be casual as well as one slows down the haemodynamic and other pathophysiological disorders.
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