Related Experiment Video
Updated: Jul 20, 2026

11:15
fMRI Mapping of Brain Activity Associated with the Vocal Production of Consonant and Dissonant Intervals
Published on: May 23, 2017
The irradiated larynx and voice: a perceptual study
Summary
Radiotherapy for laryngeal cancer reduced voice dysphonia, but post-treatment voices remained distinct from healthy controls. Voice quality improved, shifting towards normal after treatment.
Area of Science:
- Otolaryngology
- Speech-Language Pathology
- Radiation Oncology
Background:
- Laryngeal cancer significantly impacts vocal function.
- Radiotherapy is a common treatment modality for laryngeal cancer.
- Understanding the long-term effects of radiotherapy on voice is crucial for patient quality of life.
Purpose of the Study:
- To perceptually evaluate voice changes in male patients with laryngeal cancer after radiotherapy.
- To quantify the severity and predominant quality of dysphonia before and after treatment.
- To compare post-treatment voices with those of a healthy control group.
Main Methods:
- Perceptual evaluation of male patients' voices sampled pre-treatment and 1 year post-radiotherapy.
- Interval scaling of dysphonia severity by eight trained listeners.
- Identification of predominant voice qualities (e.g., rough, normal).
- Comparison with a control group of male subjects.
Main Results:
- Pre-treatment voices exhibited the highest degree of dysphonia.
- Radiotherapy led to a significant decrease in dysphonia severity.
- Post-treatment voices were not fully indistinguishable from control group voices.
- Over 50% of irradiated patients showed improved voice qualities (rough or normal) post-radiotherapy.
Conclusions:
- Radiotherapy effectively reduces dysphonia in laryngeal cancer patients.
- Vocal function improvement occurs post-treatment, but some vocal deviations may persist.
- Voice quality shifts towards normal parameters following radiotherapy, indicating treatment efficacy.
Related Concept Videos
Perception of Sound Waves
The human ear is not equally sensitive to all frequencies in the audible range. It may perceive sound waves with the same pressure but different frequencies as having different loudness. Moreover, the perception of sound waves depends on the health of an individual's ears, which decays with age. The health of one's ears may also be affected by regular exposure to loud noises.
The pitch of a sound depends on the frequency and the pressure amplitude of the source. Two sounds of the same frequency...
The pitch of a sound depends on the frequency and the pressure amplitude of the source. Two sounds of the same frequency...
Larynx
The human larynx, often referred to as the voice box, is an intricate organ located in the neck. It serves as a pathway for air to enter the lungs during respiration and is an essential component of voice production.
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids, corniculates, and...
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids, corniculates, and...
Respiratory System Abnormal Finding II: Palpation and Auscultation
In assessing respiratory abnormalities, palpation and auscultation are critical tools for detecting and interpreting various pathophysiological changes. These techniques provide insight into underlying disorders by evaluating tactile sensations and sounds produced by the respiratory system.
Palpation Findings
During a respiratory assessment, palpation can reveal several vital abnormalities:
Palpation Findings
During a respiratory assessment, palpation can reveal several vital abnormalities:
Auditory Perception
The auditory system is essential for sound perception, utilizing various critical structures. When sound waves enter the outer ear, they travel through the ear canal and cause the eardrum to vibrate. These vibrations are then transmitted to the middle ear, where three tiny bones – the malleus, incus, and stapes – amplify the sound. This amplification is crucial, as it ensures that the sound vibrations are strong enough to be conveyed to the inner ear. These vibrations then reach the cochlea, a...
Perceiving Loudness, Pitch, and Location
The human brain perceives pitch through two primary mechanisms reflected in place theory and frequency theory. Each mechanism describes how sound waves are interpreted as specific pitches by the brain, offering insights into the intricate processes of auditory perception.
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by identifying...
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by identifying...
Factors Affecting Perception
Perception is influenced by perceptual set, context, motivation, and emotion. Perceptual set, or perceptual expectancy, refers to the tendency to perceive things in a particular way, influenced by previous experiences and expectations. This phenomenon affects the interpretation of stimuli, creating a set of mental tendencies and assumptions that impact sensory perceptions of sound, taste, touch, and sight.
An illustrative example of a perceptual set is the scenario where an airline pilot told...
An illustrative example of a perceptual set is the scenario where an airline pilot told...

