Concentrations of cefazolin sodium in ischemic extremities

Patients with ischemic extremities were administered 2 g of cefazolin sodium (CEZ) intravenously from the unaffected extremity. Blood samples were periodically taken from both affected and unaffected extremities and concentrations of CEZ in both samples were compared. No statistically significant difference was observed in the concentration of CEZ in affected and unaffected extremities, which suggested that systematic administration of CEZ has satisfactory effects on ischemic extremities.