Related Experiment Video
Updated: Aug 10, 2026

Fabrication and Implantation of Miniature Dual-element Strain Gages for Measuring In Vivo Gastrointestinal Contractions in Rodents.
Published on: September 18, 2014
Abstract:
Signals for meal termination are traced to the stomach rather than duodenum or mouth when rats eat familiar food. Two types of signal occur, one measuring amount of nutrient independent of volume or dilution, the other gastric distention. The signals concerning the second ascend the vagus. Nutrient content is measured by some product of the digestive breakdown of the nutrient. The nutrient signals have to be calibrated through a process of learning. The gastric signals generated by food with a novel flavor are disregarded and oropharyngeal cues assume control instead. Finally, evidence against the role of cholecystokinin and bombesin in satiety is presented.
Related Concept Videos
Hormonal Regulation
Stomach pH Regulation
The acid-secreting gastric mucosal epithelial cells (parietal cells) lining the stomach lumen maintain the low pH in the lumen. Numerous ion transporters and channels on these parietal...
Regulation of the Digestive System
The effectors in this regulation system are glands and smooth muscles. Activation of these...
Gross Anatomy of the Stomach
Gastric Phase of Digestion
When food enters the stomach, it stretches the stomach walls and activates stretch receptors. This triggers local reflexes of the enteric nervous system, mediated through the myenteric plexus. These...
Peptic Ulcer Disease V: Surgical Management and Nursing Care
Surgical Interventions for Peptic Ulcer Disease

