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Haematological studies on vegans.

T A Sanders, F R Ellis, J W Dickerson

    The British Journal of Nutrition
    |July 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Vegan diets are generally adequate for normal blood formation, preventing megaloblastic anemia. Supplementation with vitamin B12 is recommended for optimal health outcomes in vegan individuals.

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    Area of Science:

    • Nutritional Science
    • Hematology

    Background:

    • Investigating the hematological status of vegans is crucial due to potential nutrient deficiencies.
    • Understanding the impact of plant-based diets on blood parameters is essential for public health.

    Purpose of the Study:

    • To assess vitamin B12 and folate levels in caucasian vegans and compare them to omnivore controls.
    • To evaluate the prevalence of anemia and blood count abnormalities in a vegan population.

    Main Methods:

    • Serum and erythrocyte concentrations of vitamin B12 and folate were measured.
    • Full blood counts and blood film analyses were performed on all participants.
    • Comparison between vegan and omnivore groups, considering vitamin B12 supplementation and fortified foods.

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    Main Results:

    • All vegans exhibited normal blood counts and hemoglobin levels; megaloblastic anemia was rare.
    • Male vegans showed lower erythrocyte counts and higher mean corpuscular volume/hemoglobin.
    • Vegans had higher serum folate levels; vitamin B12 levels were lower but within normal ranges, especially in non-supplemented individuals.

    Conclusions:

    • A well-planned vegan diet, rich in diverse plant foods and supplemented with vitamin B12, supports normal blood formation.
    • Megaloblastic anemia is uncommon in caucasian vegans adhering to a balanced plant-based diet.
    • Dietary folate is generally abundant in vegan diets, while vitamin B12 status requires attention, particularly without supplementation.