Increased content of saliva cortisol following infusion of ioglycamate

The release of steroid hormones from protein bound stores by ioglycamide has previously been confirmed by clinical and experimental findings. Increased saliva cortisol levels were observed following intravenous infusion of ioglycamate. Saliva cortisol content was measured before and after ioglycamide infusion in routine clinical examinations. The saliva steroid level has been shown to concur well with the serum level of free steroids. Thus, the increase of cortisol in saliva would indicate the release of cortisol from serum proteins by ioglycamate.