Related Experiment Videos
Methotrexate induced alteration of glycolysis in L1210 cells in vitro
Biomedicine / [Publiee Pour L'A.A.I.C.I.G.]
|April 1, 1978
Abstract:
Methotrexate, in non-lethal doses, greatly enhances anaerobic glycolysis in L1210 cells. Lactate/glucose ratio remains constant but intracellular levels of glycolytic enzymes are increased. ATP accumulating in the cells seems to reflect an alteration of regulation of the glycolysis.