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Stable nitrones from 17 beta-Hydroxylamine derivatives of 8 beta- and 8 alpha-estrone
Steroids
|July 1, 1983
Abstract:
17 beta-Hydroxylamine derivatives of 8 beta and 8 alpha-estrone can be obtained by reduction of the corresponding oximes with diborane or NaCNBH3. The products can be converted easily and reversibly to nitrones by addition of aldehydes or ketones. The nitrones are more stable than the corresponding hydroxylamines, and may be used as protecting groups.
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