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Updated: Sep 21, 2026

Non-invasive Assessment of Microvascular and Endothelial Function
Published on: January 29, 2013
[The blood flow in the peripheral arterial occlusive disease--investigation by 133Xe clearance method]
Abstract:
The blood flow in the lower extremities was investigated before and after surgery on patients with peripheral arterial occlusive disease by 133Xe clearance method in order to evaluate results of sympathectomy and reconstructive arterial surgery. Sixty-four patients, 54 with arteriosclerosis obliterans, 7 with thromboangiitis obliterans and 3 with Raynaud's disease were divided in two groups. Skin blood flow was measured in one group and muscle blood flow in another one. Flow was measured at rest in the former, while at rest, during and after exercise in the latter. The following results were obtained. The preoperative clearance was correlated with severity of the disease. Skin blood flow increased after sympathectomy more than reconstructive arterial surgery. Muscle blood flow before and after reconstructive surgery increased adequately at rest and under reactive hyperemia. The 133Xe clearance method is a simple and reliable test for evaluation of the blood flow in the extremities.
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