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Classification of potentially toxic chemicals based on their effects on mitochondrial respiration
Physiological Chemistry and Physics and Medical NMR
|January 1, 1983
Abstract:
The classification of potentially toxic chemicals including environmental pollutants was made with respect to state 3 and state 4 respiration of mitochondria. The concentration of certain metals for 50% inhibition of respiratory control index (RCI; state 3/state 4) was lower than that of organic compounds tested. Various chemicals including environmental pollutants were classified into four groups by combination of effects on state 3 and state 4 respiration.