[A controlled study on the effects of nomifensine treatment of depression in the elderly]

After a description of the pharmacological and therapeutic properties of Nomifensine, the results obtained by administering the drug to 40 elderly patients suffering from depression are reported. A double blind test with a placebo was conducted in two separate stages. Dosage was 70-75 mg per diem. Effects were evaluated on a slightly modified Plutchik scale. The drug alleviated depressive symptoms to a statistically significant greater degree than the placebo. Subjective side effects were minimal. No A.P. or biohumoral changes were observed.