[Loss of neurons in the granular layer of the cerebellum in epilepsy]

Morphometric examination of the neurons in the cerebellar granular layer in epilepsy showed a significant mean decrease in their number. There is no correlation between this reduction and the duration of epilepsy or frequency of seizures, respectively. The pattern of lesions reach from slight patchy cell loss to severe diffuse reduction of neurons. The diameters of the granular neuronal nuclei showed a great variability. There is no correlation between age and the distribution of these diameters.