Replication of hog cholera virus in porcine alveolar macrophage cultures

Eight hog cholera viral strains were tested for virulence for pigs and ability to replicate in porcine alveolar macrophage cultures. Of them, five were virulent and replicated well in the macrophage culture. The other three were avirulent and grew less remarkably in this culture than them. It was suggested that the ability of the hog cholera viral strains to replicate in porcine macrophages might be correlated with their virulence.