Related Experiment Video

Updated: Aug 18, 2026

Human In Vitro Suppression as Screening Tool for the Recognition of an Early State of Immune Imbalance
14:01

Human In Vitro Suppression as Screening Tool for the Recognition of an Early State of Immune Imbalance

Published on: July 22, 2011

Serum clearance rates of immunologically reactive thyroglobulin

P L Gerfo, T Colacchio, D Colacchio

    Cancer
    |July 1, 1978
    PubMed

    More Related Videos

    Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation11:49

    Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation

    Published on: May 2, 2013

    Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model04:39

    Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

    Published on: March 17, 2023

    Related Concept Videos

    Drug Elimination: The Concept of Clearance01:06

    Drug Elimination: The Concept of Clearance

    Drug elimination refers to removing drugs from the body, either through urine by the kidneys or through bile by the liver. Drug clearance is a pharmacokinetic parameter that measures the efficiency of drug removal from the bloodstream within a specific time frame. It is calculated as the rate at which a drug is eliminated from plasma divided by the plasma concentration of the drug.
    Drug clearance is not limited to renal excretion but encompasses all organs involved in drug elimination,...
    Renal Clearance01:23

    Renal Clearance

    The glomerular filtration rate (GFR) is a critical marker of kidney function, reflecting the efficiency of filtration by the glomeruli. Renal clearance of specific substances, such as inulin or creatinine, is commonly used to measure GFR.
    Renal clearance refers to the volume of plasma cleared of a specific substance, such as creatinine, per unit of time. To measure clearance, urine samples are collected over a 24-hour period during each bladder voiding, followed by a single blood sample at the...
    Renal Drug Clearance: Comparison Between Renal Excretion Methods01:08

    Renal Drug Clearance: Comparison Between Renal Excretion Methods

    Renal clearance is a critical parameter encompassing kidney filtration, secretion, and reabsorption processes. It is calculated using a specific equation to determine the rate at which the kidneys clear a drug.
    Renal clearance is often associated with the renal glomerular filtration rate (GFR), which represents the rate at which plasma is filtered through the glomeruli in the kidney. When drug reabsorption is minimal and there is no active secretion, renal clearance is closely related to the...
    Hepatic Drug Clearance: Restrictive and Nonrestrictive Clearance01:09

    Hepatic Drug Clearance: Restrictive and Nonrestrictive Clearance

    Hepatic clearance refers to the volume of blood cleared of a drug by the liver per unit of time. It plays a crucial role in drug metabolism and elimination. While hepatic clearance is commonly estimated by subtracting renal clearance from total body clearance, other pathways, such as pulmonary or biliary clearance, may also contribute. However, these pathways are generally less significant than hepatic and renal clearance.
    Most drugs undergo restrictive clearance, which is proportional to the...
    Drug Dosing in Renal Diseases: Measurement of Serum Creatinine Concentration and Clearance01:25

    Drug Dosing in Renal Diseases: Measurement of Serum Creatinine Concentration and Clearance

    In healthy individuals, serum creatinine levels remain stable due to a balance between its constant production—primarily from muscle metabolism—and renal excretion. Creatinine is freely filtered by the glomeruli, making it a valuable marker for estimating renal function. When the glomerular filtration rate (GFR) decreases, the kidneys can only eliminate less creatinine, causing serum levels to rise.Serum creatinine concentration is widely used to estimate creatinine clearance (Clcr), a...