A summary of the results of screening for HLA antibodies for one year

In one year, 748 serum specimens from obstetric patients were screened for HLA antibodies. Of the 284 showing antibody activity, 179 were nonspecific and 68 were multispecific. Thirty-seven (5%) were found to be monospecific, representing 11 specificities, of which the most common were anti-B7, -B8, -A2, and -B12. Recovery of antisera for reagent use was financially feasible.