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Related Experiment Videos

Glucose intolerance in an employed population.

E Mikuni, T Ohoshi, K Hayashi

    The Tohoku Journal of Experimental Medicine
    |December 1, 1983
    PubMed
    Summary

    Occupational roles influence glucose intolerance. Managers had higher rates due to diet and low exercise, while laborers had lower rates, though shift work increased diabetes risk.

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    Area of Science:

    • Occupational Health
    • Endocrinology
    • Metabolic Syndrome

    Background:

    • Glucose intolerance prevalence varies across occupational groups.
    • Environmental factors like diet, exercise, and stress are implicated in metabolic health.
    • Shift work is a potential stressor affecting physiological parameters.

    Purpose of the Study:

    • To investigate the relationship between occupational roles and glucose intolerance.
    • To identify environmental factors contributing to glucose intolerance in male factory workers.
    • To examine the impact of shift work on physiological markers related to glucose metabolism.

    Main Methods:

    • Cross-sectional study of approximately 9000 male factory workers across different occupational groups (laborers, clerks, managers).
    • Analysis of age- and weight-adjusted prevalence rates of glucose intolerance.
    • Assessment of dietary intake, physical activity levels, and work shift patterns.
    • Measurement of urinary excretion of hormones and metabolites (HGH, VMA, 170HCS, CPR) in a subset of laborers.

    Main Results:

    • Prevalence of glucose intolerance was 3.2% in laborers, 5.8% in clerks, and 9.3% in managers.
    • Managers exhibited excessive calorie intake, low complex carbohydrates, and high animal fat intake.
    • Laborers showed lower glucose intolerance prevalence, attributed to higher exercise levels.
    • Diabetes prevalence was higher in laborers working all three shifts (2.1%) compared to day shifts (0.9%).
    • Midnight shift work was associated with significantly higher urinary HGH and VMA, and lower 170HCS compared to day shifts.

    Conclusions:

    • Occupational status, exercise, nutrition, and stress significantly impact glucose intolerance.
    • Shift work and associated physiological changes may contribute to metabolic disturbances.
    • Environmental and lifestyle factors are critical determinants of glucose intolerance in the workplace.

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