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Thyroid abnormalities in diabetes mellitus.

M Nakazono, M Kudo, T Baba

    The Tohoku Journal of Experimental Medicine
    |December 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

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    Thyroid issues like goiters and antibodies are common in diabetes mellitus patients. Aged diabetics may develop atrophic autoimmune thyroiditis, potentially leading to subclinical hypothyroidism.

    Area of Science:

    • Endocrinology
    • Immunology
    • Diabetology

    Background:

    • Diabetes mellitus is a common endocrine disorder.
    • Thyroid dysfunction, including goiters and autoimmune thyroiditis, can coexist with diabetes.
    • Understanding the relationship between diabetes and thyroid health is crucial for comprehensive patient care.

    Purpose of the Study:

    • To investigate the incidence of goiters and thyroid antibodies in patients with diabetes mellitus.
    • To examine the correlation between these thyroid conditions, age, and diabetes management.
    • To explore the potential link to atrophic autoimmune thyroiditis and subclinical hypothyroidism in aged diabetics.

    Main Methods:

    • Studied 278 patients with diabetes mellitus, excluding those with primary hypothyroidism.

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  • Measured serum TSH concentrations.
  • Assessed the incidence of goiters, microsome antibodies, and thyroglobulin antibodies, analyzing data by age and gender.

    • Main Results:

    • Goiter incidence was 31.8%, higher in females and younger diabetics (<40 years).
    • Microsome antibody incidence was 18.5%, with varied prevalence across age groups.
    • Goiter and antibody incidence was independent of diabetes treatment; however, goiters decreased with age while thyroid antibodies and TSH levels increased.

    Conclusions:

    • Aged diabetics show an increased incidence of thyroid antibodies and TSH levels, alongside a decreased goiter rate.
    • Findings suggest a potential for atrophic autoimmune thyroiditis and subclinical hypothyroidism in older individuals with diabetes.
    • Highlights the importance of monitoring thyroid function in diabetic patients, particularly the elderly.