Cutaneous angiosarcoma resembling anaplastic Kaposi's sarcoma in a homosexual man

A 46-year-old man presented with an unusual angiosarcoma of skin and urinary bladder, clinically suggestive of Kaposi's sarcoma (KS). Histologically, the pattern was that of an anaplastic angiosarcoma with only minimal regions considered characteristic of KS. It is suggested that this rare type of angiosarcoma may be closely related to, if not best classified as, an anaplastic variant of KS. The cutaneous lesions responded to intralesional vinblastine. The association of anaplastic angiosarcoma with homosexual sexual practices should be investigated along with those cases having the classical histologic characteristics of Kaposi's sarcoma.