Malignant tumors of the vagina. Classification and approach to treatment

While primary carcinoma of the vagina is relatively rare, metastatic lesions arising from the endometrium are more common, and extension from cervical or vulvar tumors can also affect the vagina. Adenocarcinoma related to diethylstilbestrol exposure in utero is a recently recognized type of vaginal lesion, and melanoma and sarcoma occur rarely in the vagina. Familiarity on the physician's part with these various presentations and their proper management will help ensure early treatment and preservation of normal vaginal function in affected patients.