Acute myopathy associated with gasoline sniffing

Acute myopathy and myoglobinuria with markedly elevated creatine kinase (CK) activity developed in an 18-year-old boy on two occasions after gasoline sniffing. No signs of CNS involvement were seen, and the symptoms receded in a few days. The amount of lead in blood and urine exceeded the reference value for subjects with occupational exposure. The component of gasoline that was responsible for the myopathy remains unknown. Acute myoglobinuria appears to be a rare complication of gasoline sniffing.