[Porphyria cutanea tarda caused by methotrexate and buthiopurine therapy]

In a patient with psoriatic erythroderma treated with Methotrexate and later with Buthiopurine, porphyrinuria and later porphyria cutanea tarda developed, following a toxic reaction with bone marrow suppression. Hepatological examination before therapy did not reveal any signs of active liver disease.