[Neuropharmacology of stress analgesia]

Painful and non-painful stresses have a different line of action on analgetic activity of phentanyl. Hyperalgetic action of immobilization stress is supposed to be linked with impairment of the functioning of the thalamocortical serotonin-sensitive system that gets activated before the development of maximal analgesia in non-stressed cats. Droperidol reduces the antinociceptive action of painful stress. Melipramine and tisercin potentiate stress analgesia.