Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Stunted growth].

J R Bierich

    Monatsschrift Kinderheilkunde : Organ Der Deutschen Gesellschaft Fur Kinderheilkunde
    |April 1, 1983
    PubMed
    Summary

    Growth hormone (GH) deficiency causes over half of growth disorders, including hypothalamo-pituitary dwarfism and constitutional delay. Treatment with GH and anabolics is effective for several conditions.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Constitutional delay of growth and adolescence. Results of short-term and long-term treatment with GH.

    Acta endocrinologica·1992
    Same author

    Aetiology and pathogenesis of growth hormone deficiency.

    Bailliere's clinical endocrinology and metabolism·1992
    Same author

    Constitutional delay of growth and adolescence.

    Bailliere's clinical endocrinology and metabolism·1992
    Same author

    [The treatment of aging subjects with growth hormone].

    Zeitschrift fur Gerontologie·1991
    Same author

    New observations on midline defects: coincidence of anophthalmos, microphthalmos and cryptophthalmos with hypothalamic disorders.

    European journal of pediatrics·1991
    Same author

    [Growth hormone profile in constitutional and acquired developmental delay].

    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde·1990

    Area of Science:

    • Pediatric Endocrinology
    • Growth Hormone Research
    • Developmental Biology

    Context:

    • Over half of growth disorders stem from growth hormone (GH) deficiency.
    • Understanding the diverse etiologies of growth retardation is crucial for effective management.
    • Distinguishing between various causes of short stature is essential for appropriate therapeutic strategies.

    Purpose:

    • To delineate the causes of growth disorders, focusing on GH deficiency.
    • To differentiate classic hypothalamo-pituitary dwarfism from constitutional delay and other conditions.
    • To discuss the therapeutic applications of GH and anabolics in managing growth impairments.

    Summary:

    • Classic hypothalamo-pituitary dwarfism results from hypothalamic lesions, tumors, malformations, or hereditary GH-synthesis defects.
    • Constitutional delay of growth presents with harmonious delays in growth, skeletal, and sexual maturation, often with diminished spontaneous GH secretion.
    • Impaired GH synthesis, familial short stature, intrauterine growth retardation, and genetic disorders represent other significant causes of growth retardation, with varying prognoses and treatment considerations.

    Impact:

    • Provides a comprehensive overview of growth disorders and their underlying mechanisms.
    • Highlights the diagnostic challenges in differentiating various causes of short stature.
    • Informs clinical practice regarding the therapeutic potential of growth hormone and anabolic agents.

    Related Experiment Videos