Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Myoclonic dystonia.

J A Obeso, J C Rothwell, A E Lang

    Neurology
    |July 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Idiopathic torsion dystonia combined with myoclonic jerks presents diagnostic challenges. Myoclonus likely originates subcortically, with visible jerks being part of dystonia's involuntary movement spectrum.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Refining a mouse model of progressive supranuclear palsy through inoculation of human post-mortem brain-derived tau.

    BMC research notes·2026
    Same author

    Opinions and clinical practices related to diagnosing and managing functional (psychogenic) movement disorders: changes in the last decade.

    European journal of neurology·2020
    Same author

    Tremor with congenital mirror movements: evidence of involvement of the primary motor cortex in tremor.

    European journal of neurology·2019
    Same author

    Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy.

    Movement disorders : official journal of the Movement Disorder Society·2017
    Same author

    Targeted delivery of an ADP-ribosylating bacterial toxin into cancer cells.

    Scientific reports·2017
    Same author

    Neurologic diagnostic criteria for functional neurologic disorders.

    Handbook of clinical neurology·2016

    Area of Science:

    • Neurology
    • Movement Disorders
    • Clinical Neuroscience

    Background:

    • Idiopathic torsion dystonia is a neurological movement disorder.
    • Myoclonic jerks are sudden, brief, involuntary muscle contractions.
    • Co-occurrence of these conditions can complicate diagnosis.

    Purpose of the Study:

    • To investigate the characteristics of myoclonic jerks in patients with idiopathic torsion dystonia.
    • To understand the relationship between myoclonus and dystonia in affected individuals.
    • To clarify diagnostic challenges posed by this combined presentation.

    Main Methods:

    • Study included 14 patients with idiopathic torsion dystonia and myoclonic jerks.
    • Clinical observation focused on the interplay between dystonic postures and myoclonic movements.

    Related Experiment Videos

  • Electroencephalography (EEG) was used to investigate potential time-locked events preceding jerks.

    • Main Results:

    • In many patients, the same muscles exhibited both dystonia and myoclonus.
    • Myoclonic jerks were brief (50-200 msec), irregular, and often involved antagonist muscle cocontraction.
    • Jerks frequently superimposed on sustained dystonic contractions; no time-locked EEG event preceded jerks.

    Conclusions:

    • The combination of idiopathic torsion dystonia and myoclonic jerks can lead to misdiagnosis of other dyskinesias.
    • Myoclonus in this context likely originates from a subcortical focus.
    • Visible jerks are probably an integral part of the involuntary movement spectrum in torsion dystonia.