Comparative measurements of urinary polyamines in early morning and 24-hour urine specimens

Detailed comparative measurements of urinary polyamines were made between an early morning spot urine and 24-hour urine from normal controls and from patients with cancers. Urinary putrescine and spermidine concentrations in samples of morning spot urine were similar to those in 24-hour urine samples, and they were significantly increased in patients with various types of cancer. A morning spot urine can replace 24-hour urine in polyamine assay.