[Genetic relationship between the neurological (excitability thresholds) and the behavioral characteristics of mouse strains and their hybrids]

The comparative genetic analysis of 16 inbred mouse strains was carried out for excitability thresholds of peripherical parts of the nervous system, viability to learning, short-term memory and exploratory activity in different experimental conditions. The high positive correlation was shown between excitability thresholds of different parts of the peripherical nervous system, the high negative correlation being established between excitability thresholds, viability to learning, short-term memory and exploratory activity. The data led to the conclusion about the existence of the pleiotropic effect of genes controlling the excitability thresholds, on peculiarities of behaviour. This was confirmed by the findings obtained in the study of various hybrids, which point to the similar way of inheritance of excitability thresholds and behavioural patterns.