Androgen influences on glucosamine 6-phosphate synthase in the epididymis of the rat

Glucosamine 6-phosphate synthase activity in the total, caput, and cauda epididymis was estimated. Efferent duct ligation for 7 or 16 days caused significant reduction in the enzyme activity of caput epididymidis only and had no effect on the cauda epididymidis. Treatment with dihydrotestosterone (DHT) at a dose of 100 micrograms per day restored the enzyme activity in the caput epididymidis.