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[Acquired neonatal herpes].

G Damon, J Bourgeois, J C Berthier

    Archives Francaises De Pediatrie
    |June 1, 1983
    PubMed
    Summary
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    Neonatal herpes simplex virus type I infection in a newborn resolved favorably with early Acyclovir treatment. This case highlights the importance of prompt antiviral therapy for localized neonatal herpes to prevent severe complications.

    Area of Science:

    • Neonatal infections
    • Virology
    • Pediatric infectious diseases

    Background:

    • Neonatal herpes simplex virus (HSV) infection poses significant risks, including dissemination and neurological complications.
    • Primary maternal HSV infection during pregnancy or delivery is a major transmission route.
    • Early diagnosis and intervention are crucial for favorable outcomes.

    Observation:

    • A case of neonatal herpes simplex virus type I infection is presented with a positive outcome.
    • The infant received Acyclovir treatment from the onset of rash, avoiding meningo-encephalitis or dissemination.
    • Diagnosis was confirmed via vesicle scraping and serologic studies in both infant and mother.

    Findings:

    • The infection was traced to primary maternal gingivostomatitis occurring on the day of delivery.

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  • Early Acyclovir treatment was associated with a favorable clinical course in localized neonatal herpes.
  • The study reviews neonatal HSV contamination routes and risks of dissemination.

    • Implications:

    • Prompt antiviral treatment, such as Acyclovir, is recommended for all neonates with localized HSV infection.
    • Preventing HSV transmission in maternity hospitals and newborn nurseries is critical.
    • Early intervention can significantly improve outcomes and reduce morbidity in neonatal herpes cases.