[Effect of pregnancy on the state of the hemostatic system in intact and thymectomized rats]

Thymectomized rats developed hypercoagulation and inhibition of fibrinolysis. At the same time such animals showed a tendency towards a higher aggregation of platelets and enhanced antiaggregation activity of the vascular wall. Pregnant rats, both intact and thymectomized, exhibited hypocoagulation and inhibition of fibrinolysis. It is believed that the lack of differences in the hemostasis might be accounted for by activation of secretory function of the thymus in fetuses of pregnant thymectomized rats.