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Torulopsis glabrata perinephric abscess.

R B Khauli, S Kalash, J D Young

    The Journal of Urology
    |November 1, 1983
    PubMed
    Summary

    A rare Torulopsis glabrata perinephric abscess, originating from an ascending route infection, presents diagnostic challenges. Early surgical and antifungal treatment, potentially including ketoconazole, is crucial for patient outcomes.

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    Area of Science:

    • Nephrology
    • Infectious Diseases
    • Mycology

    Background:

    • Perinephric abscesses are serious kidney infections.
    • Torulopsis glabrata is a yeast pathogen.
    • This specific fungal abscess has not been previously documented.

    Observation:

    • The pathogenesis involves an ascending route infection.
    • This leads to papillary necrosis and microabscess formation.
    • These microabscesses extend into the perinephric space.

    Findings:

    • Preoperative diagnosis of this condition is challenging.
    • Increased clinical awareness is essential for timely identification.
    • Treatment requires a combination of surgical intervention and systemic antifungal therapy.

    Implications:

    • This study highlights a novel clinical presentation of Torulopsis glabrata infection.
    • It emphasizes the need for considering fungal etiologies in complex perinephric abscesses.
    • The discussion of ketoconazole suggests its potential role in managing such infections.

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