Focal cerebral ischemia and mitral valve prolapse in monozygotic twins

Mitral valve prolapse (MVP) is a common frequently inherited cardiac valvular disorder. Ischemic cerebrovascular disease (ICVD) is an apparent complication of MVP. We report the concordance of MVP and ICVD in a pair of monozygotic twins. This occurrence reinforces the concepts that MVP is highly concordant in monozygotic twins and that it can be the cause of familial ICVD.