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Diurnal changes and reproducibility of corrected sinus node recovery time
Catheterization and Cardiovascular Diagnosis
|January 1, 1983
Summary
Corrected sinus node recovery time (CSRT) testing for sick sinus syndrome is more reliable when using higher atrial overdrive stimulation rates (AST) of 140 bpm or more. Optimal diagnostic yield depends on both the time of day and the specific AST employed.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Diagnostics
Background:
- Corrected sinus node recovery time (CSRT) is a diagnostic measure for sick sinus syndrome.
- Previous studies suggest CSRT may be unreliable in identifying all cases.
Purpose of the Study:
- To assess the influence of time of day and atrial overdrive stimulation (AST) rates on CSRT measurements.
- To determine optimal conditions for CSRT testing in diagnosing sick sinus syndrome.
Main Methods:
- Evaluated CSRT in 15 patients with sick sinus syndrome over three days.
- Utilized varying AST rates (90-200 bpm) and recorded measurements at multiple time points throughout the day.
- Employed a loop-mounted stable atrial electrode for consistent stimulation.
Main Results:
- CSRT values were consistently prolonged (≥560 msec) only with AST ≥140 bpm.
- Reproducibility of CSRT measurements was confirmed at AST ≥140 bpm across days (P>.05).
- CSRT values showed significant day-to-day variation at lower AST rates (90 and 110 bpm, P<.05).
Conclusions:
- Higher AST rates (≥140 bpm) improve the reliability and reproducibility of CSRT testing.
- The time of day and the specific AST rate significantly impact the diagnostic accuracy of CSRT for sick sinus syndrome.