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Updated: Aug 15, 2026

Methods for Quantitative Detection of Antibody-induced Complement Activation on Red Blood Cells
Published on: January 29, 2014
Complement in thrombotic thrombocytopenic purpura
This report describes a patient with recurrent thrombotic thrombocytopenic purpura (TTP) in whom complement activation was observed during the acute episodes. Serum C3, C4, and CH50 were reduced, and there was deposition of C3 on red cells and platelets. These findings returned to normal during clinical remission.
This report describes a patient with recurrent thrombotic thrombocytopenic purpura (TTP) in whom complement activation was observed during the acute episodes. Serum C3, C4, and CH50 were reduced, and there was deposition of C3 on red cells and platelets. These findings returned to normal during clinical remission.
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