[Clinical course of pregnancy and labor following in-vitro fertilization]

Data of 11 pregnancies (1 twin-pregnancy - 12 deliveries) achieved by in-vitro-fertilization and embryotransfer on infertile patients are reported. For most patients pregnancy was almost normal; 2 patients had threatened premature labour. In 5 cases there was evidence of moderate EPH-gestosis. In many of the women excessive weight gain was observed although estriol and human chorionic somatotrophin values were within the normal range. Intrauterine growth was normal according to echographic cephalometry. In 4 pregnancies delivery was by cesarean section after spontaneous onset of labour. All newborn babies were healthy and developed normally. The sex ratio was 7: 5 girls to boys (including one set of female twins). From fertilization the duration of the pregnancies was 265 +/- 5 days which corresponds with previous calculations based on the monitoring of ovulation. Calculated from implantation, presumably 5 days after fertilization, duration of pregnancy was 260 +/- 5 days.