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Influence of impairment of the immune system on hepatic biotransformation reactions, their postnatal development and
Experimental Pathology
|January 1, 1983
Abstract:
Neither destruction of thymus by N-methylnitrosourea or by X-rays nor thymectomy or splenectomy in rats of different ages affected hexobarbital sleeping time, ethylmorphine N-demethylation or ethoxycoumarin O-deethylation significantly and systematically. Thymectomy or thymus destruction by x-rays of newborn rats did not significantly influence postnatal development or inducibility by phenobarbital of the monooxygenase reactions.