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Updated: Aug 19, 2026

Visualizing and Quantifying Pharmaceutical Compounds within Skin using Coherent Raman Scattering Imaging
Published on: November 24, 2021
Biological evaluation of Wratizolin penetration from ointments to the skin
Abstract:
The degree of Wratizolin penetration to the skin from ointments prepared in 6 different media was determined. Experiments were carried out in mice and guinea pigs using: a) method determining the decrement of cytotoxic and antibacterial activity of the tested ointment contacted with the skin, b) biological tests to check the presence-of the drug in tissue extracts. Absorption of Wratizolin appeared dependent upon the kind of base ointment. The preparation penetrated well when suspended in polyethylene glycol base ointment (PEG).
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