Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

2.7K
Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
2.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Finite-size correction scheme for supercell calculations in Dirac-point two-dimensional materials.

Scientific reports·2018
Same author

Brain infarcts in the arterial border zones: Clinical-pathologic correlations.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2015
Same author

Successful organ transplantation from donors poisoned with a carbamate insecticide.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2010
Same author

Malignant hyperthermia in a liver transplant patient: a case report.

Transplantation proceedings·2007
Same author

Difference invulnerability of cerebral arterial bifurcation and straight portion for development of endothelial damage.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2007
Same author

Analysis of temporal and spatial dichotomous PM air samples in the El Paso-Cd. Juarez air quality basin.

Journal of the Air & Waste Management Association (1995)·2001
Same journal

Assessing Human Epidermal Growth Factor Receptor 2 in Urothelial Carcinoma: Insights From Clinical Practice Into Scoring Criteria, Histologic Subtypes, and Genomic Characteristics Across Disease Sites.

Archives of pathology & laboratory medicine·2026
Same journal

Cross-Reactivity of TPIT Antibody Clone OTI2G1 in Chordoma: Structural Mechanisms and Diagnostic Implications.

Archives of pathology & laboratory medicine·2026
Same journal

Paracoccidioidomycosis at Autopsy: A Case Series and Literature Review.

Archives of pathology & laboratory medicine·2026
Same journal

Accuracy of Cytology Diagnosis for Well Differentiated Neuroendocrine Tumors: Assessment by the College of American Pathologists Non-Gynecologic Slide Program.

Archives of pathology & laboratory medicine·2026
Same journal

Serum Immunofixation Electrophoresis Guidance Conflict: A Call to Harmonize.

Archives of pathology & laboratory medicine·2026
Same journal

In Reply.

Archives of pathology & laboratory medicine·2026
See all related articles

Related Experiment Video

Updated: Jan 4, 2026

Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
07:56

Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats

Published on: April 21, 2017

10.9K

Ischemic injuries of the brain. Morphologic evolution.

J H Garcia

    Archives of Pathology & Laboratory Medicine
    |April 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Brain injury from arterial occlusion or cardiac arrest follows predictable patterns. Analyzing lesion location and cellular response helps determine the cause and timing of ischemic brain damage.

    More Related Videos

    Photothrombotic Ischemia: A Minimally Invasive and Reproducible Photochemical Cortical Lesion Model for Mouse Stroke Studies
    08:40

    Photothrombotic Ischemia: A Minimally Invasive and Reproducible Photochemical Cortical Lesion Model for Mouse Stroke Studies

    Published on: June 9, 2013

    36.7K
    The Hypoxic Ischemic Encephalopathy Model of Perinatal Ischemia
    08:47

    The Hypoxic Ischemic Encephalopathy Model of Perinatal Ischemia

    Published on: November 18, 2008

    36.3K

    Related Experiment Videos

    Last Updated: Jan 4, 2026

    Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
    07:56

    Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats

    Published on: April 21, 2017

    10.9K
    Photothrombotic Ischemia: A Minimally Invasive and Reproducible Photochemical Cortical Lesion Model for Mouse Stroke Studies
    08:40

    Photothrombotic Ischemia: A Minimally Invasive and Reproducible Photochemical Cortical Lesion Model for Mouse Stroke Studies

    Published on: June 9, 2013

    36.7K
    The Hypoxic Ischemic Encephalopathy Model of Perinatal Ischemia
    08:47

    The Hypoxic Ischemic Encephalopathy Model of Perinatal Ischemia

    Published on: November 18, 2008

    36.3K

    Area of Science:

    • Neurology
    • Pathology
    • Neuroscience

    Background:

    • Ischemic brain injury results from diverse mechanisms.
    • Understanding these mechanisms is crucial for diagnosis and treatment.
    • Predicting the cause and age of brain lesions aids clinical management.

    Purpose of the Study:

    • To analyze the topographic distribution and cellular responses of brain lesions.
    • To predict the approximate age and cause of ischemic brain injury.
    • To differentiate between arterial and venous infarcts and global ischemia.

    Main Methods:

    • Analysis of lesion topography in the brain.
    • Evaluation of cellular responses to ischemia.
    • Correlation of lesion characteristics with potential causes (arterial occlusion, cardiac arrest, increased intracranial pressure).

    Main Results:

    • Arterial occlusions caused pale or hemorrhagic infarcts in specific arterial territories.
    • Venous infarcts exhibited more extensive hemorrhage than arterial infarcts.
    • Transient global ischemia (e.g., cardiac arrest) led to multifocal lesions affecting all brain components.
    • Nonocclusive global ischemia from increased intracranial pressure caused distinct injury patterns.

    Conclusions:

    • Brain injury patterns are diverse but predictable based on ischemic mechanism.
    • Topographic analysis and cellular responses are key to determining the cause and age of ischemic lesions.
    • Distinguishing between different types of ischemic injury is possible through detailed pathological examination.