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Updated: Aug 11, 2026

05:10
Gasless Endoscopic Thyroidectomy via the Trans-Axillary Approach
Published on: September 15, 2023
Summary
Subtotal thyroidectomy is the preferred treatment for thyrotoxicosis, showing fewer complications than radio-iodine therapy. Surgery resulted in 70% of patients being complication-free and euthyroid, with lower risks compared to radio-iodine.
Area of Science:
- Endocrinology
- Surgical Oncology
- Nuclear Medicine
Background:
- Radio-iodine therapy is increasingly suggested for all thyrotoxicosis cases.
- Subtotal thyroidectomy is a traditional surgical approach for hyperthyroidism.
- Long-term outcomes and complication rates of surgical intervention require evaluation.
Purpose of the Study:
- To evaluate the efficacy and safety of subtotal thyroidectomy for thyrotoxicosis.
- To compare surgical outcomes with reported radio-iodine treatment results.
- To analyze complication rates and long-term euthyroid status post-surgery.
Main Methods:
- Retrospective analysis of 627 patients undergoing subtotal thyroidectomy.
- Mean follow-up period of 5.8 years.
- Assessment of complications including hypothyroidism, recurrent thyrotoxicosis, hypocalcemia, and vocal cord palsy.
Main Results:
- Subtotal thyroidectomy resulted in 26.6% hypothyroidism and 2.6% recurrent thyrotoxicosis.
- Permanent hypocalcemia occurred in 1.4% of patients; vocal cord palsy in 0.2%.
- Approximately 70% of patients were complication-free and euthyroid post-surgery.
Conclusions:
- Subtotal thyroidectomy remains a favorable treatment option for thyrotoxicosis.
- Surgical outcomes demonstrate a high rate of euthyroid status and manageable complications.
- Radio-iodine therapy may lead to universal hypothyroidism and carries concerns regarding malignancy.

