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Related Experiment Videos

Surgery for thyrotoxicosis.

J M Simms, C H Talbot

    The British Journal of Surgery
    |October 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Subtotal thyroidectomy is the preferred treatment for thyrotoxicosis, showing fewer complications than radio-iodine therapy. Surgery resulted in 70% of patients being complication-free and euthyroid, with lower risks compared to radio-iodine.

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    Area of Science:

    • Endocrinology
    • Surgical Oncology
    • Nuclear Medicine

    Background:

    • Radio-iodine therapy is increasingly suggested for all thyrotoxicosis cases.
    • Subtotal thyroidectomy is a traditional surgical approach for hyperthyroidism.
    • Long-term outcomes and complication rates of surgical intervention require evaluation.

    Purpose of the Study:

    • To evaluate the efficacy and safety of subtotal thyroidectomy for thyrotoxicosis.
    • To compare surgical outcomes with reported radio-iodine treatment results.
    • To analyze complication rates and long-term euthyroid status post-surgery.

    Main Methods:

    • Retrospective analysis of 627 patients undergoing subtotal thyroidectomy.
    • Mean follow-up period of 5.8 years.

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  • Assessment of complications including hypothyroidism, recurrent thyrotoxicosis, hypocalcemia, and vocal cord palsy.

    • Main Results:

    • Subtotal thyroidectomy resulted in 26.6% hypothyroidism and 2.6% recurrent thyrotoxicosis.
    • Permanent hypocalcemia occurred in 1.4% of patients; vocal cord palsy in 0.2%.
    • Approximately 70% of patients were complication-free and euthyroid post-surgery.

    Conclusions:

    • Subtotal thyroidectomy remains a favorable treatment option for thyrotoxicosis.
    • Surgical outcomes demonstrate a high rate of euthyroid status and manageable complications.
    • Radio-iodine therapy may lead to universal hypothyroidism and carries concerns regarding malignancy.