Related Experiment Video

Updated: Aug 14, 2026

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
08:57

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Published on: August 14, 2018

Structural and evolutionary analysis of the two chimpanzee alpha-globin mRNAs

S A Liebhaber, K A Begley

    Nucleic Acids Research
    |December 20, 1983
    PubMed
    Summary

    Researchers identified two chimpanzee alpha-globin messenger RNAs (mRNAs), finding structural similarities to human alpha-globin mRNAs. This suggests recent gene conversion in human alpha-globin genes and varied evolutionary rates within the alpha-globin gene family.

    More Related Videos

    Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin11:17

    Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin

    Published on: March 10, 2021

    An Integrated Approach for Microprotein Identification and Sequence Analysis09:37

    An Integrated Approach for Microprotein Identification and Sequence Analysis

    Published on: July 12, 2022

    Related Concept Videos

    Gene Evolution - Fast or Slow?02:05

    Gene Evolution - Fast or Slow?

    The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
    In contrast, regions which code...
    Protein Families02:47

    Protein Families

    Protein families are groups of homologous proteins; that is, they have similarities in amino acid sequences and three-dimensional structures. Protein families usually occur because of gene duplication, where an additional copy of a gene is inserted into the genome of an organism.   Mutations that change the amino acids but still allow the protein to be properly synthesized, will lead to new protein family members.   If these new proteins contain similar amino acids in key locations, protein...
    Evolutionary Relationships through Genome Comparisons02:54

    Evolutionary Relationships through Genome Comparisons

    Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
    Multi-species Conserved Sequences02:51

    Multi-species Conserved Sequences

    Next-generation sequencing technologies have created large genomic databases of a variety of animals and plants. Ever since the human genome project was completed, scientists studied the genome of primates, mammals, and other phylogenetically distant living beings. Such large-scale  studies have provided new insights into the evolutionary relationship between organisms.
    Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved DNA...
    Gene Duplication and Divergence02:37

    Gene Duplication and Divergence

    The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was  generated by gene duplication and divergence, indicating its critical role in evolution.
    The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are characterized.
    Gene Evolution - Fast or Slow?02:05

    Gene Evolution - Fast or Slow?

    The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
    In contrast, regions which code...