Related Experiment Video
Updated: Aug 16, 2026

Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli
Published on: September 25, 2016
Thromboembolic complications after combined internal carotid ligation and extra- to-intracranial bypass
Insights
Therapeutic internal carotid artery occlusion, often with bypass surgery, may lead to embolic complications. These emboli frequently occlude the middle cerebral artery, causing ischemic events.
Area of Science:
- Neurosurgery
- Vascular Surgery
- Neurology
Background:
- Therapeutic occlusion of the internal carotid artery is a neurosurgical procedure.
- Extracranial-to-intracranial bypass is sometimes performed in conjunction with carotid occlusion.
- Embolic complications are a known risk associated with vascular interventions.
Purpose of the Study:
- To summarize cases of embolic complications during or after internal carotid artery occlusion.
- To investigate the potential role of extracranial-to-intracranial bypass in these complications.
- To review the literature on ischemic complications of surgical carotid occlusion.
Main Methods:
- A brief summary of twelve cases of probable embolic complication.
- Data collected via an informal survey of 30 neurosurgeons.
- Literature review focusing on surgical carotid occlusion and ischemic complications.
Main Results:
- Twelve cases of embolic complications were identified in patients who underwent internal carotid artery occlusion and bypass.
- In most cases, the middle cerebral artery was occluded by an embolus.
- Emboli likely originated from the occluded internal carotid artery or treated aneurysm.
Conclusions:
- Embolic complications, particularly middle cerebral artery occlusion, are a significant risk of therapeutic internal carotid artery occlusion, even with bypass.
- The pathogenesis of these emboli requires further investigation.
- Understanding the frequency and causes of ischemic complications is crucial for patient management.
Abstract:
Twelve cases of probable embolic complication occurring during or after therapeutic occlusion of the internal carotid artery are summarized briefly. In each case, an extracranial-to-intracranial bypass procedure had been performed. These cases were collected from an informal survey of 30 neurosurgeons. In most instances, the middle cerebral artery became occluded as a result of an embolus, probably formed in the occluded internal carotid artery or possibly in the giant aneurysm being treated. The literature on surgical carotid occlusion is reviewed, with particular emphasis on the frequency and pathogenesis of ischemic complications.
Related Concept Videos
The Arch of Aorta
Encircling the heart, the coronary arteries form a ring-like structure before...
Aneurysm III: Interprofessional Care
Venous Thrombosis I: Introduction
Venous Thrombosis III: Interprofessional Care
Ischemic Stroke l: Introduction

