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Related Experiment Videos

Transient oculomotor synkinesis in temporal arteritis.

P A Sibony, S Lessell

    Archives of Neurology
    |January 1, 1984
    PubMed
    Summary

    Temporal arteritis can cause ophthalmoplegia, leading to oculomotor synkinesis. This suggests nerve damage, not muscle issues, due to aberrant axon regeneration in the third nerve.

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    Area of Science:

    • Neuroscience
    • Ophthalmology
    • Rheumatology

    Background:

    • Temporal arteritis (giant cell arteritis) is an inflammatory condition affecting large and medium-sized arteries.
    • Ophthalmoplegia, or paralysis of eye muscles, can be a rare complication of temporal arteritis.

    Observation:

    • A patient with temporal arteritis presented with ophthalmoplegia.
    • The patient also exhibited transient oculomotor synkinesis, a condition involving aberrant regeneration of the third cranial nerve.

    Findings:

    • The presence of synkinesis suggests a neurogenic origin for the ophthalmoplegia, differentiating it from a myogenic cause.
    • Published experimental data supports the hypothesis that aberrant regeneration of axons within the third nerve causes transient oculomotor synkinesis.

    Implications:

    • This case highlights a potential neurogenic mechanism for ophthalmoplegia in temporal arteritis.
    • Understanding aberrant regeneration in the third nerve is crucial for diagnosing and managing ocular complications in vasculitis patients.

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