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Adenocarcinoid (mucinous carcinoid) of the appendix
Gastroenterology
|February 1, 1984
Summary
Appendiceal adenocarcinoids are rare tumors with mixed carcinoid and adenocarcinoma features. These tumors exhibit aggressive behavior, necessitating distinct classification and management strategies.
Area of Science:
- Gastroenterology
- Surgical Pathology
- Oncology
Background:
- Appendiceal carcinoid tumors are common incidental findings.
- Appendiceal tumors with mixed carcinoid and adenocarcinoma histology are rare.
- The biologic behavior of these mixed tumors remains unclear.
Purpose of the Study:
- To characterize the clinical and histologic features of appendiceal tumors with combined carcinoid and adenocarcinoma features.
- To differentiate these rare tumors from ordinary appendiceal carcinoids.
- To evaluate the clinical behavior and outcomes of these unique appendiceal neoplasms.
Main Methods:
- Retrospective review of 10 cases of appendiceal tumors with mixed carcinoid and adenocarcinoma features.
- Analysis of patient demographics, clinical presentation, surgical procedures, and pathologic findings.
- Correlation of histologic features with clinical outcomes, including metastasis and survival.
Main Results:
- Ten cases were identified among 45 appendiceal tumors (1960-1982).
- Patients presented with symptoms of acute appendicitis or abdominal mass.
- Tumor invasion and metastasis (lymph node, ovarian) were observed; 1 patient died, 2 had persistent disease, and 5 were disease-free post-surgery.
Conclusions:
- Appendiceal tumors with mixed carcinoid and adenocarcinoma histology are distinctive.
- These lesions exhibit more aggressive behavior than typical carcinoids but less than adenocarcinomas.
- Classification as 'adenocarcinoids' is supported due to their unique clinicopathologic profile.
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